DNA-Analytik

    Molecular Biodiversity Research

    Our research projects focus on a combination of field ecology with bioinformatics and new sequencing technologies. Conceptually, we are very interested in patterns and structuring forces of communities, where organisms are not easily identifiable or distinguishable from each other. This interest applies to various levels, starting with abundance and diversity of taxa, over phylogenetic reconstructions, towards environmental and spatial influences and lastly regarding organisms' molecular interactions with each other on a genomic level. Methodologically, the workgroup is developing computational workflows and databases as well as laboratory protocols to analyse ecological samples with next-generation sequencing technologies. 

    Biologically, the focus of current projects is the dynamics of bacteria-host associations in changing environments. Regarding this, we currently consider changes in microbiota induced by 

    • symbiotic host-host interactions (vectorization through pollination),
    • the host's development (flowering),
    • geographic intra-specific variability  (toxicity of poison dart frogs),
    • climatic changes (bee nests along altitudinal gradients),
    • prey capturing (carnivorous plants, reptiles),
    • other behavioral actions (cryptobiosis in tardigrades, ecdysis in reptiles), 

    as well as general variation between tissues and species of hosts (solitary bees, vascular plants). 

    To answer these questions, we conduct field work, analyse samples in our molecular laboratory and apply computational approaches. We have successfully developed methods to simultaneously assess biodiversity of bacteria and plants (here:~mixed pollen samples) through next-generation sequencing allowing a very fine scaled interpretation of plant-bee-microbe interactions. Usually we start with descriptive studies, investigating the status-quo, which are followed by experimental designs manipulating the associations by (e.g.~antibiotic) exclusion and bioassays. Lastly, for prospective bacteria with interesting distributions and activity, we are also engaged into genomics, studying the genetic possibilities that bacteria bring into the associations with their respective hosts.

    We are happy to announce that we will host a summerschool this year on "Plant and Pollen Metabarcoding" together with a Mini-Symposium of the "PollenBoL" group of researchers. The short outline is:

    • Laboratory Workshop: 9-10. May 2016, 9 AM to 6 PM
    • Bioinformatics Workshop: 11-12. May 2016, 9 AM to 6 PM
    • Mini-Symposium: 13. May 2016, 10 AM to 6 PM
    • Registration for each of the three parts is separate due to different space limitations
    • Scholarships: available for students and early postdocs
    • Application closes on 31. January 2016 

    More Details here

    Kontakt

    Molecular Biodiversity Group
    Department of Animal Ecology and Tropical Biology
    Am Hubland
    97074 Würzburg

    Tel.: +49 931 31-84427
    Fax: +49 931 31-84352
    E-Mail

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    Hubland Süd, Geb. B1